STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fleNEquals llo1127; similar to flagellar synthesis regulator. (289 aa)    
Predicted Functional Partners:
fliA
Sigma factor 28; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
 
  
 0.985
flgD
Flagellar basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
 
  
 0.914
fleR
Equals llo2319; similar to two-component response regulator.
 
 
 0.871
fleQ
Transcriptional regulator FleQ; Equals llo2013.
 
 
 0.848
LLO_3125
Regulatory protein (GGDEF and EAL domains); Equals llo3125.
 
 
 0.795
LLO_1253
Regulatory protein (GGDEF domain); Equals llo1253.
 
 
 0.794
LLO_3302
Putative chemotaxis histidine kinase; Equals llo3302.
 
  
 0.733
fleS
Equals llo2320; similar to sensor histidine kinase.
 
   
 0.725
cheB
Fused chemotaxis regulator; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
  
 0.693
LLO_3084
Putative two-component response regulator; Equals llo3084.
  
 
 0.499
Your Current Organism:
Legionella longbeachae
NCBI taxonomy Id: 661367
Other names: L. longbeachae NSW150, Legionella longbeachae NSW150, Legionella longbeachae str. NSW150, Legionella longbeachae strain NSW150
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.