murA protein (Legionella longbeachae) - STRING interaction network

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murA

UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (422 aa)

Predicted Functional Partners:

murB

0.960

glmU

0.952

wecB

0.912

LLO_0236

0.906

capL

0.903

lpxA

0.892

LLO_2017

0.851

murC

0.848

murE

0.816

murF

0.806

Your Current Organism:

Legionella longbeachae

NCBI taxonomy Id: 661367
Other names: L. longbeachae NSW150, Legionella longbeachae NSW150, Legionella longbeachae str. NSW150, Legionella longbeachae strain NSW150

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LLO_0236	capL	LLO_0236	LLO_0383	Putative NAD dependent epimerase/dehydratase; Equals llo0236.	Protein capL; Equals llo0383; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	0.924
LLO_0236	glmU	LLO_0236	LLO_0190	Putative NAD dependent epimerase/dehydratase; Equals llo0236.	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.914
LLO_0236	lpxA	LLO_0236	LLO_2684	Putative NAD dependent epimerase/dehydratase; Equals llo0236.	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.807
LLO_0236	murA	LLO_0236	LLO_2016	Putative NAD dependent epimerase/dehydratase; Equals llo0236.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.906
LLO_0236	wecB	LLO_0236	LLO_0217	Putative NAD dependent epimerase/dehydratase; Equals llo0236.	UDP-N-acetylglucosamine 2-epimerase; Equals llo0217; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	0.989
LLO_2017	murA	LLO_2017	LLO_2016	Equals llo2017; similar to conserved hypothetical protein; Belongs to the BolA/IbaG family.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.851
capL	LLO_0236	LLO_0383	LLO_0236	Protein capL; Equals llo0383; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	Putative NAD dependent epimerase/dehydratase; Equals llo0236.	0.924
capL	glmU	LLO_0383	LLO_0190	Protein capL; Equals llo0383; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.926
capL	lpxA	LLO_0383	LLO_2684	Protein capL; Equals llo0383; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.823
capL	murA	LLO_0383	LLO_2016	Protein capL; Equals llo0383; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.903
capL	wecB	LLO_0383	LLO_0217	Protein capL; Equals llo0383; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	UDP-N-acetylglucosamine 2-epimerase; Equals llo0217; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	0.987
glmU	LLO_0236	LLO_0190	LLO_0236	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Putative NAD dependent epimerase/dehydratase; Equals llo0236.	0.914
glmU	capL	LLO_0190	LLO_0383	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Protein capL; Equals llo0383; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	0.926
glmU	lpxA	LLO_0190	LLO_2684	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.848
glmU	murA	LLO_0190	LLO_2016	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.952
glmU	murC	LLO_0190	LLO_2756	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.579
glmU	murE	LLO_0190	LLO_0858	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.	0.711
glmU	wecB	LLO_0190	LLO_0217	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylglucosamine 2-epimerase; Equals llo0217; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.	0.942
lpxA	LLO_0236	LLO_2684	LLO_0236	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	Putative NAD dependent epimerase/dehydratase; Equals llo0236.	0.807
lpxA	capL	LLO_2684	LLO_0383	UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	Protein capL; Equals llo0383; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.	0.823

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