Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vhtDHydrogenase expression/formation protein; Equals llo2452. (164 aa)    
Predicted Functional Partners:
LLO_2450
Equals llo2450; similar to coenzyme F420-reducing hydrogenase, gamma subunit.
 
  
 0.967
LLO_2451
Equals llo2451; similar to coenzyme F420-reducing hydrogenase, alpha subunit.
 
  
 0.966
LLO_2448
Equals llo2448; similar to hydrogenase subunit.
 
   
 0.962
hydG
Hydrogenase/sulfur reductase gamma subunit; Equals llo2449; similar to 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.
 
    0.956
hypC
Hydrogenase expression/formation protein HypC; Equals llo2445.
  
  
 0.773
hypD
Hydrogenase expression/formation protein HypD; Equals llo2446; Belongs to the HypD family.
     
 0.755
hypE
Hydrogenase expression/formation protein HypE; Equals llo2447.
     
 0.755
hypF
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.751
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
  
 0.717
hypB
Hydrogenase expression/formation protein HypB; Equals llo2443.
  
  
 0.712
Your Current Organism:
Legionella longbeachae
NCBI taxonomy Id: 661367
Other names: L. longbeachae NSW150, Legionella longbeachae NSW150, Legionella longbeachae str. NSW150, Legionella longbeachae strain NSW150
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