STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KUO03991.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)    
Predicted Functional Partners:
KUO03905.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.877
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
    
 0.810
KUO06252.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.760
KUN91431.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.760
KUO04061.1
Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.751
KUN97428.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.744
KUN93702.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.714
KUO03189.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.697
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.695
KUN97494.1
Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.673
Your Current Organism:
Streptomyces caeruleatus
NCBI taxonomy Id: 661399
Other names: CCTCC M 208213, NRRL B-24802, S. caeruleatus, Streptomyces caeruleatus Zhu et al. 2011, Streptomyces sp. GIMN4.002, strain GIMN4.002
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