node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KUN95377.1 | KUN95381.1 | AQJ67_35885 | AQJ67_35910 | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
KUN95377.1 | guaB | AQJ67_35885 | AQJ67_26505 | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.979 |
KUN95381.1 | KUN95377.1 | AQJ67_35910 | AQJ67_35885 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
KUN95381.1 | guaA | AQJ67_35910 | AQJ67_26585 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.426 |
KUN95381.1 | guaB | AQJ67_35910 | AQJ67_26505 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.955 |
KUN95381.1 | ribBA | AQJ67_35910 | AQJ67_30305 | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.534 |
KUN95486.1 | KUN98930.1 | AQJ67_35015 | AQJ67_26510 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.908 |
KUN95486.1 | KUO02030.1 | AQJ67_35015 | AQJ67_22860 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.902 |
KUN95486.1 | KUO03905.1 | AQJ67_35015 | AQJ67_14185 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.774 |
KUN95486.1 | guaA | AQJ67_35015 | AQJ67_26585 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.965 |
KUN95486.1 | guaB | AQJ67_35015 | AQJ67_26505 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.961 |
KUN95486.1 | purA | AQJ67_35015 | AQJ67_37770 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.960 |
KUN95486.1 | purH | AQJ67_35015 | AQJ67_26745 | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
KUN98930.1 | KUN95486.1 | AQJ67_26510 | AQJ67_35015 | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.908 |
KUN98930.1 | KUO02030.1 | AQJ67_26510 | AQJ67_22860 | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.923 |
KUN98930.1 | KUO03905.1 | AQJ67_26510 | AQJ67_14185 | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.728 |
KUN98930.1 | guaA | AQJ67_26510 | AQJ67_26585 | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.998 |
KUN98930.1 | guaB | AQJ67_26510 | AQJ67_26505 | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.983 |
KUN98930.1 | purA | AQJ67_26510 | AQJ67_37770 | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.986 |
KUN98930.1 | purH | AQJ67_26510 | AQJ67_26745 | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.960 |