| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIE84304.1 | AIE84305.1 | OP10G_0936 | OP10G_0937 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.999 |
| AIE84304.1 | AIE84306.1 | OP10G_0936 | OP10G_0938 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.998 |
| AIE84304.1 | AIE84330.1 | OP10G_0936 | OP10G_0962 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Siroheme synthase; Belongs to the precorrin methyltransferase family. | 0.974 |
| AIE84304.1 | AIE86633.1 | OP10G_0936 | OP10G_3265 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Putative glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.821 |
| AIE84304.1 | hemA | OP10G_0936 | OP10G_0935 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.997 |
| AIE84304.1 | hemE | OP10G_0936 | OP10G_0941 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.978 |
| AIE84304.1 | hemH | OP10G_0936 | OP10G_0943 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.606 |
| AIE84304.1 | hemL | OP10G_0936 | OP10G_0940 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.923 |
| AIE84305.1 | AIE84304.1 | OP10G_0937 | OP10G_0936 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| AIE84305.1 | AIE84306.1 | OP10G_0937 | OP10G_0938 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.992 |
| AIE84305.1 | AIE84330.1 | OP10G_0937 | OP10G_0962 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Siroheme synthase; Belongs to the precorrin methyltransferase family. | 0.997 |
| AIE84305.1 | AIE86633.1 | OP10G_0937 | OP10G_3265 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Putative glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.409 |
| AIE84305.1 | hemA | OP10G_0937 | OP10G_0935 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.930 |
| AIE84305.1 | hemE | OP10G_0937 | OP10G_0941 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.934 |
| AIE84305.1 | hemL | OP10G_0937 | OP10G_0940 | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde-2,1-aminomutase. | 0.697 |
| AIE84306.1 | AIE84304.1 | OP10G_0938 | OP10G_0936 | Porphobilinogen synthase; Belongs to the ALAD family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
| AIE84306.1 | AIE84305.1 | OP10G_0938 | OP10G_0937 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.992 |
| AIE84306.1 | AIE84330.1 | OP10G_0938 | OP10G_0962 | Porphobilinogen synthase; Belongs to the ALAD family. | Siroheme synthase; Belongs to the precorrin methyltransferase family. | 0.851 |
| AIE84306.1 | AIE84868.1 | OP10G_0938 | OP10G_1500 | Porphobilinogen synthase; Belongs to the ALAD family. | Malonyl CoA-acyl carrier protein transacylase. | 0.637 |
| AIE84306.1 | AIE86633.1 | OP10G_0938 | OP10G_3265 | Porphobilinogen synthase; Belongs to the ALAD family. | Putative glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.983 |