node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIE85623.1 | AIE85624.1 | OP10G_2255 | OP10G_2256 | Xanthine/uracil/vitamin C permease. | 4-hydroxybenzoyl-CoA thioesterase. | 0.492 |
AIE85623.1 | guaA | OP10G_2255 | OP10G_3839 | Xanthine/uracil/vitamin C permease. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.417 |
AIE85623.1 | guaB | OP10G_2255 | OP10G_2965 | Xanthine/uracil/vitamin C permease. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.418 |
AIE85623.1 | purC | OP10G_2255 | OP10G_2930 | Xanthine/uracil/vitamin C permease. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.416 |
AIE85623.1 | purD | OP10G_2255 | OP10G_3443 | Xanthine/uracil/vitamin C permease. | Phosphoribosylamine/glycine ligase; Belongs to the GARS family. | 0.426 |
AIE85623.1 | purE | OP10G_2255 | OP10G_2933 | Xanthine/uracil/vitamin C permease. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.431 |
AIE85623.1 | purK | OP10G_2255 | OP10G_2345 | Xanthine/uracil/vitamin C permease. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.422 |
AIE85623.1 | purL | OP10G_2255 | OP10G_3721 | Xanthine/uracil/vitamin C permease. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.436 |
AIE85623.1 | purQ | OP10G_2255 | OP10G_2157 | Xanthine/uracil/vitamin C permease. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.405 |
AIE85624.1 | AIE85623.1 | OP10G_2256 | OP10G_2255 | 4-hydroxybenzoyl-CoA thioesterase. | Xanthine/uracil/vitamin C permease. | 0.492 |
guaA | AIE85623.1 | OP10G_3839 | OP10G_2255 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Xanthine/uracil/vitamin C permease. | 0.417 |
guaA | guaB | OP10G_3839 | OP10G_2965 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purC | OP10G_3839 | OP10G_2930 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.687 |
guaA | purD | OP10G_3839 | OP10G_3443 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylamine/glycine ligase; Belongs to the GARS family. | 0.874 |
guaA | purE | OP10G_3839 | OP10G_2933 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.558 |
guaA | purK | OP10G_3839 | OP10G_2345 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.626 |
guaA | purL | OP10G_3839 | OP10G_3721 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.843 |
guaA | purQ | OP10G_3839 | OP10G_2157 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.664 |
guaB | AIE85623.1 | OP10G_2965 | OP10G_2255 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Xanthine/uracil/vitamin C permease. | 0.418 |
guaB | guaA | OP10G_2965 | OP10G_3839 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |