STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C440_03913COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). (215 aa)    
Predicted Functional Partners:
C440_09022
uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase.
 
 
 0.997
C440_14044
Hypothetical protein.
  
 
 0.986
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.944
C440_03908
Heme biosynthesis protein nirH/G (nirL/nirD-like protein); COG1522 Transcriptional regulators.
 
  
 0.935
hemD
COG1587 Uroporphyrinogen-III synthase.
 
 
 0.846
C440_09017
COG0181 Porphobilinogen deaminase.
 
 
 0.824
C440_06237
COG2875 Precorrin-4 methylase.
 
  
 0.821
C440_06242
COG2073 Cobalamin biosynthesis protein CbiG.
 
  
 0.805
C440_06297
cobalt-precorrin-6Y C(5)-methyltransferase; COG2241 Precorrin-6B methylase 1.
 
  
 0.747
C440_08982
COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.747
Your Current Organism:
Haloferax mucosum
NCBI taxonomy Id: 662479
Other names: H. mucosum ATCC BAA-1512, Haloferax mucosum ATCC BAA-1512, Haloferax mucosum JCM 14792, Haloferax mucosum PA12, Haloferax sp. PA12
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