node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C440_04243 | C440_14264 | C440_04243 | C440_14264 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | 0.994 |
C440_04243 | C440_14269 | C440_04243 | C440_14269 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | COG0015 Adenylosuccinate lyase. | 0.999 |
C440_04243 | purD | C440_04243 | C440_00345 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.995 |
C440_04243 | purE | C440_04243 | C440_14814 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | Phosphoribosylaminoimidazole carboxylase catalytic chain; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
C440_04243 | purF | C440_04243 | C440_11013 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.993 |
C440_04243 | purK | C440_04243 | C440_14819 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.983 |
C440_04243 | purL | C440_04243 | C440_14484 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.992 |
C440_04243 | purM | C440_04243 | C440_00865 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.991 |
C440_04243 | purQ | C440_04243 | C440_04263 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.991 |
C440_04243 | purS | C440_04243 | C440_04258 | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.981 |
C440_14264 | C440_04243 | C440_14264 | C440_04243 | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase. | 0.994 |
C440_14264 | C440_14269 | C440_14264 | C440_14269 | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | COG0015 Adenylosuccinate lyase. | 0.999 |
C440_14264 | purD | C440_14264 | C440_00345 | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.999 |
C440_14264 | purE | C440_14264 | C440_14814 | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | Phosphoribosylaminoimidazole carboxylase catalytic chain; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.993 |
C440_14264 | purF | C440_14264 | C440_11013 | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.998 |
C440_14264 | purK | C440_14264 | C440_14819 | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.990 |
C440_14264 | purL | C440_14264 | C440_14484 | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.998 |
C440_14264 | purM | C440_14264 | C440_00865 | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | COG0150 Phosphoribosylaminoimidazole (AIR) synthetase. | 0.999 |
C440_14264 | purQ | C440_14264 | C440_04263 | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.998 |
C440_14264 | purS | C440_14264 | C440_04258 | Bifunctional purine biosynthesis protein PurH; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN. | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.995 |