STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
moaAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (320 aa)    
Predicted Functional Partners:
moaC
Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
C440_03948
Molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; COG0303 Molybdopterin biosynthesis enzyme.
 
 0.987
C440_12364
COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein.
 
 
 0.976
C440_03953
Molybdenum cofactor synthesis protein; COG0303 Molybdopterin biosynthesis enzyme.
 
 0.964
C440_10713
Molybdenum cofactor biosynthesis protein B; COG0521 Molybdopterin biosynthesis enzymes.
 
 
 0.929
C440_11373
ATP-binding protein mrp; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.926
mptA
GTP cyclohydrolase; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
     
  0.912
C440_10553
COG1977 Molybdopterin converting factor, small subunit.
  
 
 0.890
C440_00400
COG1437 Adenylate cyclase, class 2 (thermophilic).
 
  
  0.886
ndk
Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
     
  0.861
Your Current Organism:
Haloferax mucosum
NCBI taxonomy Id: 662479
Other names: H. mucosum ATCC BAA-1512, Haloferax mucosum ATCC BAA-1512, Haloferax mucosum JCM 14792, Haloferax mucosum PA12, Haloferax sp. PA12
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