node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C440_03808 | C440_12324 | C440_03808 | C440_12324 | COG4347 Predicted membrane protein. | Hypothetical protein. | 0.626 |
C440_03808 | C440_15704 | C440_03808 | C440_15704 | COG4347 Predicted membrane protein. | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | 0.659 |
C440_03808 | C440_16259 | C440_03808 | C440_16259 | COG4347 Predicted membrane protein. | Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.701 |
C440_07407 | C440_15704 | C440_07407 | C440_15704 | Hypothetical protein. | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | 0.407 |
C440_07407 | rpl39e | C440_07407 | C440_08847 | Hypothetical protein. | COG2167 Ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. | 0.527 |
C440_12324 | C440_03808 | C440_12324 | C440_03808 | Hypothetical protein. | COG4347 Predicted membrane protein. | 0.626 |
C440_12324 | C440_15704 | C440_12324 | C440_15704 | Hypothetical protein. | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | 0.560 |
C440_12324 | C440_16259 | C440_12324 | C440_16259 | Hypothetical protein. | Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.615 |
C440_15704 | C440_03808 | C440_15704 | C440_03808 | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | COG4347 Predicted membrane protein. | 0.659 |
C440_15704 | C440_07407 | C440_15704 | C440_07407 | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | Hypothetical protein. | 0.407 |
C440_15704 | C440_12324 | C440_15704 | C440_12324 | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | Hypothetical protein. | 0.560 |
C440_15704 | C440_16259 | C440_15704 | C440_16259 | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.743 |
C440_15704 | C440_16549 | C440_15704 | C440_16549 | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases. | 0.414 |
C440_15704 | egsA | C440_15704 | C440_15519 | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | NAD(P)-dependent glycerol-1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Belongs to the glycerol-1-phosphate dehydrogenase family. | 0.737 |
C440_15704 | rpl39e | C440_15704 | C440_08847 | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | COG2167 Ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. | 0.419 |
C440_15704 | topA | C440_15704 | C440_16249 | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.453 |
C440_15704 | ubiA | C440_15704 | C440_01505 | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | Prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | 0.862 |
C440_16259 | C440_03808 | C440_16259 | C440_03808 | Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | COG4347 Predicted membrane protein. | 0.701 |
C440_16259 | C440_12324 | C440_16259 | C440_12324 | Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Hypothetical protein. | 0.615 |
C440_16259 | C440_15704 | C440_16259 | C440_15704 | Geranylgeranylglyceryl phosphate synthase-like protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. | Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold. | 0.743 |