STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C440_15744COG0350 Methylated DNA-protein cysteine methyltransferase. (151 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
       0.808
trpC
COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
       0.808
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.794
aroA-2
Fructose-bisphosphate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
       0.758
C440_07297
COG0210 Superfamily I DNA and RNA helicases.
  
   
 0.709
C440_08927
COG1199 Rad3-related DNA helicases.
 
   
 0.695
C440_12624
COG2404 Predicted phosphohydrolase (DHH superfamily).
  
     0.689
C440_00685
Hypothetical protein.
  
     0.663
dtdA
Hypothetical protein; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
 
   
 0.661
C440_11558
Hypothetical protein.
  
     0.658
Your Current Organism:
Haloferax mucosum
NCBI taxonomy Id: 662479
Other names: H. mucosum ATCC BAA-1512, Haloferax mucosum ATCC BAA-1512, Haloferax mucosum JCM 14792, Haloferax mucosum PA12, Haloferax sp. PA12
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