Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mtlDMannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)    
Predicted Functional Partners:
ANP63613.1
PTS mannitol transporter subunit IICBA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
ANP67096.1
Bifunctional PTS fructose transporter subunit IIA/HPr protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.946
scrK
Aminoimidazole riboside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.943
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
 
  
 0.942
mtlR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.917
ANP67226.1
Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.911
glpX
Fructose-1,6-bisphosphatase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.910
ANP66934.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.909
fbp
Fructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family.
     
  0.900
cmtB
PTS mannitol transporter subunit IIA; TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.727
Your Current Organism:
Vibrio alginolyticus
NCBI taxonomy Id: 663
Other names: ATCC 17749, Beneckea alginolytica, CAIM 516, CCUG 13445, CCUG 16315, CCUG 4989, CIP 103336, CIP 75.3, DSM 2171, IFO 15630, LMG 4409, LMG:4409, NBRC 15630, NCCB 71013, NCCB 77003, NCTC 12160, Oceanomonas alginolytica, Pseudomonas creosotensis, V. alginolyticus, Vibrio sp. PeIg0901
Server load: low (16%) [HD]