Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ktrBKtr system potassium transporter B; Part of the Na(+)-dependent high affinity K(+) uptake system KtrAB. KtrB is the K(+)-translocating subunit. (455 aa)    
Predicted Functional Partners:
ktrA
Potassium transporter KtrA; Part of the Na(+)-dependent high affinity K(+) uptake system KtrAB. KtrA is the regulatory subunit and plays an important role in the substrate specificity and transport mechanism of the system. Binds ATP but lacks ATPase activity.
 
 
 0.998
ktrA_2
Potassium transporter TrkA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.947
trkA
Trk system potassium transport protein TrkA; Part of a potassium transport system.
  
 
 0.817
cvrA
K+/H+ antiporter; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
     
 0.750
SapD
Peptide ABC transporter ATP-binding protein; Involved in resistance to antimibial peptides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
      
 0.721
kefB
Glutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
   
 
 0.680
ANP64031.1
Potassium transporter Kef; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.659
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
 0.610
idnT
Gluconate permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.608
ANP63658.1
Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.552
Your Current Organism:
Vibrio alginolyticus
NCBI taxonomy Id: 663
Other names: ATCC 17749, Beneckea alginolytica, CAIM 516, CCUG 13445, CCUG 16315, CCUG 4989, CIP 103336, CIP 75.3, DSM 2171, IFO 15630, LMG 4409, LMG:4409, NBRC 15630, NCCB 71013, NCCB 77003, NCTC 12160, Oceanomonas alginolytica, Pseudomonas creosotensis, V. alginolyticus, Vibrio sp. PeIg0901
Server load: medium (50%) [HD]