Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dkgB2,5-didehydrogluconate reductase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)    
Predicted Functional Partners:
ANP64174.1
PrkA family serine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.843
ANP64706.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.749
ANP67596.1
NADP-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.697
ANP63746.1
Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.695
ANP66349.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.688
rbsB
D-ribose ABC transporter substrate-binding protein RbsB; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.681
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.627
ANP67689.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 
 0.597
ANP67329.1
Thiamine biosynthesis protein ThiJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.594
ANP66966.1
Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.583
Your Current Organism:
Vibrio alginolyticus
NCBI taxonomy Id: 663
Other names: ATCC 17749, Beneckea alginolytica, CAIM 516, CCUG 13445, CCUG 16315, CCUG 4989, CIP 103336, CIP 75.3, DSM 2171, IFO 15630, LMG 4409, LMG:4409, NBRC 15630, NCCB 71013, NCCB 77003, NCTC 12160, Oceanomonas alginolytica, Pseudomonas creosotensis, V. alginolyticus, Vibrio sp. PeIg0901
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.