| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANP64013.1 | ANP66054.1 | BAU10_03105 | BAU10_14200 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.848 |
| ANP64013.1 | grpE | BAU10_03105 | BAU10_02295 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.916 |
| ANP64013.1 | hslU | BAU10_03105 | BAU10_00280 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | HslU--HslV peptidase ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.909 |
| ANP64013.1 | hslV | BAU10_03105 | BAU10_00285 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | HslU--HslV peptidase proteolytic subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.927 |
| ANP64013.1 | htpX | BAU10_03105 | BAU10_04985 | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | Zinc metalloprotease HtpX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M48B family. | 0.676 |
| ANP66054.1 | ANP64013.1 | BAU10_14200 | BAU10_03105 | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.848 |
| ANP66054.1 | aspA-2 | BAU10_14200 | BAU10_14205 | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.482 |
| ANP66054.1 | grpE | BAU10_14200 | BAU10_02295 | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.511 |
| ANP66054.1 | hslU | BAU10_14200 | BAU10_00280 | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | HslU--HslV peptidase ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.633 |
| ANP66054.1 | hslV | BAU10_14200 | BAU10_00285 | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | HslU--HslV peptidase proteolytic subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.850 |
| ANP66054.1 | htpX | BAU10_14200 | BAU10_04985 | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Zinc metalloprotease HtpX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M48B family. | 0.653 |
| ANP66054.1 | ibpA | BAU10_14200 | BAU10_15210 | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Heat-shock protein Hsp20; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the small heat shock protein (HSP20) family. | 0.596 |
| ANP66054.1 | nnrD | BAU10_14200 | BAU10_18015 | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional ADP-dependent (S)-NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-spec [...] | 0.493 |
| ANP66054.1 | trxA_2 | BAU10_14200 | BAU10_14680 | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. | 0.484 |
| ANP66054.1 | trxC | BAU10_14200 | BAU10_19950 | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioredoxin TrxC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.460 |
| aspA-2 | ANP66054.1 | BAU10_14205 | BAU10_14200 | Aspartate ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.482 |
| grpE | ANP64013.1 | BAU10_02295 | BAU10_03105 | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.916 |
| grpE | ANP66054.1 | BAU10_02295 | BAU10_14200 | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.511 |
| grpE | hslU | BAU10_02295 | BAU10_00280 | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | HslU--HslV peptidase ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.969 |
| grpE | hslV | BAU10_02295 | BAU10_00285 | Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | HslU--HslV peptidase proteolytic subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.973 |
