STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trxCThioredoxin TrxC; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)    
Predicted Functional Partners:
ANP64471.1
Thioredoxin-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.874
ANP65953.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.676
gltB
Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.658
ANP63716.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.658
ANP63764.1
Protein tyrosine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.658
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
 
  
 0.645
groEL-2
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.644
groEL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 
 0.643
ANP65208.1
Protein-tyrosine-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.626
ANP67776.1
Phosphotyrosine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.626
Your Current Organism:
Vibrio alginolyticus
NCBI taxonomy Id: 663
Other names: ATCC 17749, Beneckea alginolytica, CAIM 516, CCUG 13445, CCUG 16315, CCUG 4989, CIP 103336, CIP 75.3, DSM 2171, IFO 15630, LMG 4409, LMG:4409, NBRC 15630, NCCB 71013, NCCB 77003, NCTC 12160, Oceanomonas alginolytica, Pseudomonas creosotensis, V. alginolyticus, Vibrio sp. PeIg0901
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