STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
qnrFluoroquinolone resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)    
Predicted Functional Partners:
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
    
 
 0.825
ANP67972.1
Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.784
tlh
Thermolabile hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.741
ANP67971.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.670
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
      
 0.662
ANP67082.1
MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.649
vcrH
CesD/SycD/LcrH family type III secretion system chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.596
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.596
vscS
EscS/YscS/HrcS family type III secretion system export apparatus protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.594
vscF
EscF/YscF/HrpA family type III secretion system needle major subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.587
Your Current Organism:
Vibrio alginolyticus
NCBI taxonomy Id: 663
Other names: ATCC 17749, Beneckea alginolytica, CAIM 516, CCUG 13445, CCUG 16315, CCUG 4989, CIP 103336, CIP 75.3, DSM 2171, IFO 15630, LMG 4409, LMG:4409, NBRC 15630, NCCB 71013, NCCB 77003, NCTC 12160, Oceanomonas alginolytica, Pseudomonas creosotensis, V. alginolyticus, Vibrio sp. PeIg0901
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