STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU25865.1KEGG: cth:Cthe_0123 stage V sporulation protein AD; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein. (337 aa)    
Predicted Functional Partners:
ADU25864.1
KEGG: adg:Adeg_1248 stage V sporulation protein AC; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein.
 
  
 0.979
ADU25866.1
KEGG: amt:Amet_2221 sporulation stage V, protein AE; TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein.
 
  
 0.975
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.928
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
  
 0.840
ADU26286.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.835
ADU27028.1
Anti-sigma-factor antagonist; KEGG: afl:Aflv_1002 stage II sporulation protein AA (antagonist of anti-sigma factor, stand-alone STAS domain); TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
 
   
 0.829
ADU25880.1
KEGG: cth:Cthe_2655 AbrB family transcriptional regulator; TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain-containing protein.
  
   
 0.813
ADU28079.1
PFAM: GerA spore germination protein; KEGG: dhd:Dhaf_3282 GerA spore germination protein.
  
  
 0.797
ADU28028.1
PFAM: GerA spore germination protein; KEGG: csc:Csac_2777 GerA spore germination protein.
  
  
 0.796
ADU28251.1
RNA polymerase, sigma 28 subunit, SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
    0.796
Your Current Organism:
Ethanoligenens harbinense
NCBI taxonomy Id: 663278
Other names: E. harbinense YUAN-3, Ethanoligenens harbinense YUAN-3, Ethanoligenens harbinense str. YUAN-3, Ethanoligenens harbinense strain YUAN-3
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.