STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU25924.1(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (729 aa)    
Predicted Functional Partners:
ADU28171.1
PFAM: Ppx/GppA phosphatase; KEGG: mla:Mlab_0394 hypothetical protein.
  
 
 0.925
ADU27003.1
KEGG: bfa:Bfae_09920 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; SMART: nucleoside diphosphate kinase; Belongs to the NDK family.
    
 0.919
ADU27010.1
SMART: guanylate kinase/L-type calcium channel region; KEGG: cac:CA_C0298 guanylate kinase.
  
 
 0.918
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.918
ADU25891.1
PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; manually curated; KEGG: csc:Csac_1831 pyruvate kinase; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.909
ADU25816.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
     
 0.902
ADU27989.1
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: dhd:Dhaf_0351 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone domain protein.
     
  0.900
rpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
 
 0.895
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.863
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
 
 0.859
Your Current Organism:
Ethanoligenens harbinense
NCBI taxonomy Id: 663278
Other names: E. harbinense YUAN-3, Ethanoligenens harbinense YUAN-3, Ethanoligenens harbinense str. YUAN-3, Ethanoligenens harbinense strain YUAN-3
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