STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigARNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (372 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 0.993
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.928
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.918
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.917
ADU27900.1
Transcriptional regulator, MerR family; KEGG: bha:BH3496 transcriptional regulator of multidrug-efflux transporter genes; PFAM: regulatory protein MerR; SMART: regulatory protein MerR.
  
 
 0.877
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.876
ADU27548.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; KEGG: aoe:Clos_0999 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein.
  
 
 0.867
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
 
 
 0.746
msrB
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.694
ADU26567.1
Regulatory protein MerR; KEGG: pto:PTO0671 isochorismatase; PFAM: regulatory protein MerR; isochorismatase hydrolase; SMART: regulatory protein MerR.
  
 
 0.692
Your Current Organism:
Ethanoligenens harbinense
NCBI taxonomy Id: 663278
Other names: E. harbinense YUAN-3, Ethanoligenens harbinense YUAN-3, Ethanoligenens harbinense str. YUAN-3, Ethanoligenens harbinense strain YUAN-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.