node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADU26967.1 | coaD | Ethha_1430 | Ethha_2061 | KEGG: cce:Ccel_3188 phosphopantothenoylcysteine decarboxylase; PFAM: flavoprotein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.929 |
ADU26967.1 | coaE | Ethha_1430 | Ethha_2718 | KEGG: cce:Ccel_3188 phosphopantothenoylcysteine decarboxylase; PFAM: flavoprotein. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.409 |
ADU26967.1 | coaX | Ethha_1430 | Ethha_2180 | KEGG: cce:Ccel_3188 phosphopantothenoylcysteine decarboxylase; PFAM: flavoprotein. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.931 |
ADU26967.1 | ribBA | Ethha_1430 | Ethha_0635 | KEGG: cce:Ccel_3188 phosphopantothenoylcysteine decarboxylase; PFAM: flavoprotein. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.581 |
ADU27577.1 | ADU27579.1 | Ethha_2060 | Ethha_2062 | KEGG: tjr:TherJR_2085 hypothetical protein. | Methyltransferase; KEGG: cth:Cthe_1277 putative methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein CHP00095. | 0.897 |
ADU27577.1 | coaD | Ethha_2060 | Ethha_2061 | KEGG: tjr:TherJR_2085 hypothetical protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.830 |
ADU27579.1 | ADU27577.1 | Ethha_2062 | Ethha_2060 | Methyltransferase; KEGG: cth:Cthe_1277 putative methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein CHP00095. | KEGG: tjr:TherJR_2085 hypothetical protein. | 0.897 |
ADU27579.1 | coaD | Ethha_2062 | Ethha_2061 | Methyltransferase; KEGG: cth:Cthe_1277 putative methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein CHP00095. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.968 |
ADU27637.1 | coaD | Ethha_2120 | Ethha_2061 | PFAM: YicC-like domain-containing protein; domain of unknown function DUF1732; KEGG: cth:Cthe_1317 hypothetical protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.563 |
ADU28271.1 | coaD | Ethha_2779 | Ethha_2061 | Riboflavin biosynthesis protein RibF; KEGG: tpd:Teth39_1205 bifunctional riboflavin kinase/FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.693 |
ADU28271.1 | coaE | Ethha_2779 | Ethha_2718 | Riboflavin biosynthesis protein RibF; KEGG: tpd:Teth39_1205 bifunctional riboflavin kinase/FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.462 |
ADU28271.1 | guaA | Ethha_2779 | Ethha_1704 | Riboflavin biosynthesis protein RibF; KEGG: tpd:Teth39_1205 bifunctional riboflavin kinase/FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.429 |
ADU28271.1 | ribBA | Ethha_2779 | Ethha_0635 | Riboflavin biosynthesis protein RibF; KEGG: tpd:Teth39_1205 bifunctional riboflavin kinase/FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.677 |
coaD | ADU26967.1 | Ethha_2061 | Ethha_1430 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | KEGG: cce:Ccel_3188 phosphopantothenoylcysteine decarboxylase; PFAM: flavoprotein. | 0.929 |
coaD | ADU27577.1 | Ethha_2061 | Ethha_2060 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | KEGG: tjr:TherJR_2085 hypothetical protein. | 0.830 |
coaD | ADU27579.1 | Ethha_2061 | Ethha_2062 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Methyltransferase; KEGG: cth:Cthe_1277 putative methyltransferase; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein CHP00095. | 0.968 |
coaD | ADU27637.1 | Ethha_2061 | Ethha_2120 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | PFAM: YicC-like domain-containing protein; domain of unknown function DUF1732; KEGG: cth:Cthe_1317 hypothetical protein. | 0.563 |
coaD | ADU28271.1 | Ethha_2061 | Ethha_2779 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin biosynthesis protein RibF; KEGG: tpd:Teth39_1205 bifunctional riboflavin kinase/FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; Belongs to the ribF family. | 0.693 |
coaD | coaE | Ethha_2061 | Ethha_2718 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.950 |
coaD | coaX | Ethha_2061 | Ethha_2180 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.956 |