STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADU28180.1KEGG: cpy:Cphy_3043 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: Adenylosuccinate lyase-like; fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (477 aa)    
Predicted Functional Partners:
purC
TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: cpy:Cphy_3045 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase.
 0.997
purH
SMART: AICARFT/IMPCHase bienzyme formylation region; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: cth:Cthe_1246 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: AICARFT/IMPCHase bienzyme formylation region; MGS domain protein.
  
 0.997
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 0.997
ADU26696.1
TIGRFAM: phosphoribosylformylglycinamidine synthase; KEGG: cce:Ccel_0499 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein.
 
  
 0.992
purD
TIGRFAM: phosphoribosylamine/glycine ligase; KEGG: cth:Cthe_1245 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; Belongs to the GARS family.
  
 
 0.972
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.968
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.956
ADU27607.1
PFAM: phosphoribosyltransferase; KEGG: fnu:FN2073 adenine phosphoribosyltransferase.
  
 0.948
purM
TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; KEGG: cce:Ccel_2183 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
  
 
 0.940
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 0.934
Your Current Organism:
Ethanoligenens harbinense
NCBI taxonomy Id: 663278
Other names: E. harbinense YUAN-3, Ethanoligenens harbinense YUAN-3, Ethanoligenens harbinense str. YUAN-3, Ethanoligenens harbinense strain YUAN-3
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