| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| corC | lnt | REG_0099 | REG_0100 | Putative Mg2+ and Co2+ transporter CorC; COG4535; similar to AA sequence EcoGene EG13654; similar to AA sequence GI 188534467. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.879 |
| corC | macB | REG_0099 | REG_0880 | Putative Mg2+ and Co2+ transporter CorC; COG4535; similar to AA sequence EcoGene EG13654; similar to AA sequence GI 188534467. | Putative permease compontent of ABC-type antimicrobial peptide/macrolide transport system; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.422 |
| corC | tatB | REG_0099 | REG_0107 | Putative Mg2+ and Co2+ transporter CorC; COG4535; similar to AA sequence EcoGene EG13654; similar to AA sequence GI 188534467. | TatABCE protein translocation system subunit B; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.403 |
| corC | tatC | REG_0099 | REG_0108 | Putative Mg2+ and Co2+ transporter CorC; COG4535; similar to AA sequence EcoGene EG13654; similar to AA sequence GI 188534467. | TatABCE protein translocation system subunit C; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.403 |
| corC | yabI | REG_0099 | REG_0101 | Putative Mg2+ and Co2+ transporter CorC; COG4535; similar to AA sequence EcoGene EG13654; similar to AA sequence GI 188534467. | Conserved inner membrane protein; COG0586; similar to AA sequence EcoGene EG11571; similar to AA sequence GI 77973690. | 0.533 |
| corC | ybeY | REG_0099 | REG_0098 | Putative Mg2+ and Co2+ transporter CorC; COG4535; similar to AA sequence EcoGene EG13654; similar to AA sequence GI 188534467. | Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.821 |
| cpsB | lnt | REG_0544 | REG_0100 | Mannose-1-phosphate guanylyltransferase; COG0836; similar to AA sequence EcoGene EG10161; similar to AA sequence GI 167586362; Belongs to the mannose-6-phosphate isomerase type 2 family. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.517 |
| cpsB | yabI | REG_0544 | REG_0101 | Mannose-1-phosphate guanylyltransferase; COG0836; similar to AA sequence EcoGene EG10161; similar to AA sequence GI 167586362; Belongs to the mannose-6-phosphate isomerase type 2 family. | Conserved inner membrane protein; COG0586; similar to AA sequence EcoGene EG11571; similar to AA sequence GI 77973690. | 0.414 |
| lgt | lnt | REG_1898 | REG_0100 | Phosphatidylglycerol-prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.510 |
| lnt | corC | REG_0100 | REG_0099 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Putative Mg2+ and Co2+ transporter CorC; COG4535; similar to AA sequence EcoGene EG13654; similar to AA sequence GI 188534467. | 0.879 |
| lnt | cpsB | REG_0100 | REG_0544 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Mannose-1-phosphate guanylyltransferase; COG0836; similar to AA sequence EcoGene EG10161; similar to AA sequence GI 167586362; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.517 |
| lnt | lgt | REG_0100 | REG_1898 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Phosphatidylglycerol-prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. | 0.510 |
| lnt | macB | REG_0100 | REG_0880 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Putative permease compontent of ABC-type antimicrobial peptide/macrolide transport system; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.492 |
| lnt | pgsA | REG_0100 | REG_0553 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Phosphatidylglycerophosphate synthetase; COG0558; similar to AA sequence EcoGene EG10706; similar to AA sequence GI 123442113; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.504 |
| lnt | tatB | REG_0100 | REG_0107 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | TatABCE protein translocation system subunit B; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.487 |
| lnt | tatC | REG_0100 | REG_0108 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | TatABCE protein translocation system subunit C; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.487 |
| lnt | yabI | REG_0100 | REG_0101 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Conserved inner membrane protein; COG0586; similar to AA sequence EcoGene EG11571; similar to AA sequence GI 77973690. | 0.534 |
| lnt | ybeY | REG_0100 | REG_0098 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.696 |
| lnt | yfiO | REG_0100 | REG_1398 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Outer membrane protein assembly complex; COG4105; similar to AA sequence EcoGene EG14222; similar to AA sequence GI 77976240. | 0.545 |
| macB | corC | REG_0880 | REG_0099 | Putative permease compontent of ABC-type antimicrobial peptide/macrolide transport system; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Putative Mg2+ and Co2+ transporter CorC; COG4535; similar to AA sequence EcoGene EG13654; similar to AA sequence GI 188534467. | 0.422 |