STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (436 aa)    
Predicted Functional Partners:
purB
Adenylosuccinate lyase; COG0015; similar to AA sequence EcoGene EG11314; similar to AA sequence GI 77959454; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.996
guaB
IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 
 0.988
purL
Phosphoribosylformylglycinamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.981
purH
Fused IMP cyclohydrolase/phosphoribosylaminoimidazolecarboxamide formyltransferase; Two contigs; COG0138; similar to AA sequence EcoGene EG10795; similar to AA sequence GI 22124417.
  
 0.980
thrA
Fused aspartokinase I and homoserine dehydrogenase I; COG0527; similar to AA sequence EcoGene EG10998; similar to AA sequence GI 123440965.
  
 
 0.960
pyrB
Catalytic subunit of aspartate carbamoyltransferase; COG0540; similar to AA sequence EcoGene EG10805; similar to AA sequence GI 22124081; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.949
asnB
Asparagine synthetase B; Corrected polynucleotide track (1); COG0367; similar to AA sequence EcoGene EG10092; similar to AA sequence GI 77961554.
   
 
 0.934
aspC
PLP-dependent aspartate aminotransferase; COG1448; similar to AA sequence EcoGene EG10096; similar to AA sequence GI 218548444.
   
 0.926
nadB
Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.917
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
  
 0.879
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
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