STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsbBDisulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (174 aa)    
Predicted Functional Partners:
dsbA
Protein disulfide oxidoreductase; COG0526; similar to AA sequence EcoGene EG11297; similar to AA sequence GI 157373120.
 
 
 0.957
dsbC
Thiol:disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
 
 
 0.870
rraB
Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
  
     0.740
proQ
Putative structural transport element; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.
  
     0.719
lptC
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
   
 0.668
nlpI
TPR repeat-containing lipoprotein; COG4785; similar to AA sequence EcoGene EG12371; similar to AA sequence GI 77974024.
  
     0.640
REG_0390
Hypothetical protein; COG3092; similar to AA sequence EcoGene EG14106; similar to AA sequence GI 77956854.
  
     0.619
REG_0214
Sporulation related domain-containing protein; COG3147; similar to AA sequence EcoGene EG10218; similar to AA sequence GI 218548231.
  
     0.574
rseA
Anti-sigma factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading [...]
  
     0.562
arcB
Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063.
  
  
 0.556
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.