STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmL23S rRNA m(2)G2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (771 aa)    
Predicted Functional Partners:
uup
ATP-binding protein with possible role in replication; COG0488; similar to AA sequence EcoGene EG13134; similar to AA sequence GI 186894864.
  
  
 0.917
rluB
23S rRNA pseudouridylate synthase; COG1187; similar to AA sequence EcoGene EG12433; similar to AA sequence GI 77961373; Belongs to the pseudouridine synthase RsuA family.
  
 
 0.813
thiI
Sulfurtransferase required for thiamine and 4-thiouridine biosynthesis; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.664
pyrD
Dihydroorotate oxidase (FMN-linked); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.661
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.646
rlmB
23S rRNA (guanosine-2'-O-)-methyltransferase; COG0566; similar to AA sequence EcoGene EG12483; similar to AA sequence GI 22124552.
  
 
 0.639
arcB
Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063.
     
 0.636
typA
Putative membrane GTPase involved in stress response; COG1217; similar to AA sequence EcoGene EG11837; similar to AA sequence GI 157373111.
   
   0.632
REG_1625
ABC transporter ATP-binding protein; Corrected polynucleotide track (1); COG0488; similar to AA sequence EcoGene EG13325; similar to AA sequence GI 50121933.
  
  
 0.631
trmA
tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
  
  
 0.609
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
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