| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| REG_0682 | REG_0683 | REG_0682 | REG_0683 | ISRin1, transposase orfB; COG3293; similar to AA sequence GI 189502478. | ISRin1, transposase orfA; Similar to AA sequence GI 189502478. | 0.773 |
| REG_0682 | cmoA | REG_0682 | REG_0684 | ISRin1, transposase orfB; COG3293; similar to AA sequence GI 189502478. | Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). | 0.658 |
| REG_0683 | REG_0682 | REG_0683 | REG_0682 | ISRin1, transposase orfA; Similar to AA sequence GI 189502478. | ISRin1, transposase orfB; COG3293; similar to AA sequence GI 189502478. | 0.773 |
| REG_0683 | cmoA | REG_0683 | REG_0684 | ISRin1, transposase orfA; Similar to AA sequence GI 189502478. | Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). | 0.658 |
| REG_1034 | REG_1568 | REG_1034 | REG_1568 | Hypothetical protein; COG3319. | Permease of the major facilitator superfamily; Corrected polynucleotide track (1); COG0477; similar to AA sequence GI 22124924. | 0.452 |
| REG_1034 | arcB | REG_1034 | REG_1544 | Hypothetical protein; COG3319. | Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063. | 0.749 |
| REG_1034 | cmoA | REG_1034 | REG_0684 | Hypothetical protein; COG3319. | Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). | 0.899 |
| REG_1034 | putA | REG_1034 | REG_0691 | Hypothetical protein; COG3319. | Trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.814 |
| REG_1568 | REG_1034 | REG_1568 | REG_1034 | Permease of the major facilitator superfamily; Corrected polynucleotide track (1); COG0477; similar to AA sequence GI 22124924. | Hypothetical protein; COG3319. | 0.452 |
| REG_1568 | arcB | REG_1568 | REG_1544 | Permease of the major facilitator superfamily; Corrected polynucleotide track (1); COG0477; similar to AA sequence GI 22124924. | Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063. | 0.522 |
| REG_1568 | birA | REG_1568 | REG_0275 | Permease of the major facilitator superfamily; Corrected polynucleotide track (1); COG0477; similar to AA sequence GI 22124924. | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.414 |
| REG_1568 | cmoA | REG_1568 | REG_0684 | Permease of the major facilitator superfamily; Corrected polynucleotide track (1); COG0477; similar to AA sequence GI 22124924. | Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). | 0.406 |
| arcB | REG_1034 | REG_1544 | REG_1034 | Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063. | Hypothetical protein; COG3319. | 0.749 |
| arcB | REG_1568 | REG_1544 | REG_1568 | Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063. | Permease of the major facilitator superfamily; Corrected polynucleotide track (1); COG0477; similar to AA sequence GI 22124924. | 0.522 |
| arcB | birA | REG_1544 | REG_0275 | Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063. | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.667 |
| arcB | cmoA | REG_1544 | REG_0684 | Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063. | Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). | 0.418 |
| arcB | cmoB | REG_1544 | REG_0912 | Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063. | Putative methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | 0.426 |
| arcB | putA | REG_1544 | REG_0691 | Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063. | Trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.442 |
| arcB | ribD | REG_1544 | REG_0821 | Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.579 |
| birA | REG_1568 | REG_0275 | REG_1568 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Permease of the major facilitator superfamily; Corrected polynucleotide track (1); COG0477; similar to AA sequence GI 22124924. | 0.414 |