STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REG_0773Metallo-beta-lactamase family protein; COG0491; similar to AA sequence GI 157371107. (268 aa)    
Predicted Functional Partners:
REG_0772
NAD-dependent epimerase/dehydratase; COG0451; similar to AA sequence EcoGene EG13688; similar to AA sequence GI 157371108.
     0.934
thiI
Sulfurtransferase required for thiamine and 4-thiouridine biosynthesis; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
 0.913
REG_1683
PAS domain-containing putative transcriptional regulator; Similar to AA sequence GI 85059458.
    
   0.626
REG_1096
Putative sulfurtransferase containing rhodanese-like domain; COG0607; similar to AA sequence EcoGene EG12295; similar to AA sequence GI 77977370.
   
 0.604
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.580
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.555
ybeY
Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
    
 
 0.531
mraW
S-adenosyl-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
    
   0.528
kefB
Potassium:proton antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
   
  
 0.480
rpsQ
30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
   0.460
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.