STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
djlADnaJ-domain-containing proteins 1; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. (280 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.915
nfuA
Fe/S biogenesis protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.914
grxD
Glutaredoxin-related protein; COG0278; similar to AA sequence EcoGene EG12181; similar to AA sequence GI 77959190; Belongs to the glutaredoxin family. Monothiol subfamily.
     
 0.818
iscS
Cysteine desulfurase; COG1104; similar to AA sequence EcoGene EG12677; similar to AA sequence GI 183599754.
  
 
 0.736
lptD
Outer membrane LPS assembly complex; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
   
 0.630
radA
DNA recombination and repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
     
 0.615
fliL
Putative flagellar biogenesis protein associated with the basal body; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
    
   0.604
yfaE
2Fe-2S ferredoxin; COG0633; similar to AA sequence EcoGene EG12360; similar to AA sequence GI 77956356.
 
  
 0.586
erpA
Putative iron-sulfur cluster biosynthesis protein; COG0316; similar to AA sequence EcoGene EG12332; similar to AA sequence GI 50122228.
  
 
 0.576
sufA
Iron-sulfur cluster assembly scaffold protein; COG0316; similar to AA sequence EcoGene EG11378; similar to AA sequence GI 77975282; Belongs to the HesB/IscA family.
  
 
 0.576
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
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