STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tolRMembrane spanning protein in TolA-TolQ-TolR complex; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (142 aa)    
Predicted Functional Partners:
tolQ
Membrane spanning protein in TolA-TolQ-TolR complex; COG0811; similar to AA sequence EcoGene EG11010; similar to AA sequence GI 77960086.
 
 
 0.999
tonB
Cytoplasmic membrane protein linking inner and outer membranes; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.988
tolB
Translocation protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
  
 0.977
pal
Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.860
tolA
Cell envelope integrity inner membrane protein; COG3064; similar to AA sequence EcoGene EG11007; similar to AA sequence GI 77960084.
 
   0.826
REG_1289
Outer membrane protein assembly factor; COG4775; similar to AA sequence EcoGene EG12676; similar to AA sequence GI 77977740.
  
     0.664
yfiO
Outer membrane protein assembly complex; COG4105; similar to AA sequence EcoGene EG14222; similar to AA sequence GI 77976240.
 
    0.664
ompA
Outer membrane protein A; COG2885; similar to AA sequence EcoGene EG10669; similar to AA sequence GI 22126613.
 
 
 
 0.663
REG_0965
Hypothetical protein; COG1729; similar to AA sequence EcoGene EG12854; similar to AA sequence GI 37525409.
  
  
 0.615
motB
Flagellar motor component; COG1360; similar to AA sequence EcoGene EG10602; similar to AA sequence GI 158327337.
    
 
 0.571
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
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