| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| REG_1107 | REG_1110 | REG_1107 | REG_1110 | Hypothetical protein; COG1426; similar to AA sequence EcoGene EG10015; similar to AA sequence GI 77977353. | Hypothetical protein; COG2976; similar to AA sequence EcoGene EG14209; similar to AA sequence GI 22125254. | 0.478 |
| REG_1107 | ftsQ | REG_1107 | REG_0710 | Hypothetical protein; COG1426; similar to AA sequence EcoGene EG10015; similar to AA sequence GI 77977353. | Membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.503 |
| REG_1107 | mrdA | REG_1107 | REG_0613 | Hypothetical protein; COG1426; similar to AA sequence EcoGene EG10015; similar to AA sequence GI 77977353. | Transpeptidase involved in peptidoglycan synthesis (penicillin-binding protein 2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.549 |
| REG_1107 | mrdB | REG_1107 | REG_0614 | Hypothetical protein; COG1426; similar to AA sequence EcoGene EG10015; similar to AA sequence GI 77977353. | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.450 |
| REG_1107 | mreB | REG_1107 | REG_1235 | Hypothetical protein; COG1426; similar to AA sequence EcoGene EG10015; similar to AA sequence GI 77977353. | Actin-like component of cell wall structural complex MreBCD; COG1077; similar to AA sequence EcoGene EG10608; similar to AA sequence GI 62181882. | 0.988 |
| REG_1107 | mreC | REG_1107 | REG_1236 | Hypothetical protein; COG1426; similar to AA sequence EcoGene EG10015; similar to AA sequence GI 77977353. | Transmembrane component of cell wall structural complex MreBCD; COG1792; similar to AA sequence EcoGene EG10609; similar to AA sequence GI 145597589. | 0.540 |
| REG_1107 | mreD | REG_1107 | REG_1237 | Hypothetical protein; COG1426; similar to AA sequence EcoGene EG10015; similar to AA sequence GI 77977353. | Transmembrane component of cell wall structural complex MreBCD; COG2891; similar to AA sequence EcoGene EG10610; similar to AA sequence GI 77978747. | 0.835 |
| REG_1110 | REG_1107 | REG_1110 | REG_1107 | Hypothetical protein; COG2976; similar to AA sequence EcoGene EG14209; similar to AA sequence GI 22125254. | Hypothetical protein; COG1426; similar to AA sequence EcoGene EG10015; similar to AA sequence GI 77977353. | 0.478 |
| REG_1110 | mreD | REG_1110 | REG_1237 | Hypothetical protein; COG2976; similar to AA sequence EcoGene EG14209; similar to AA sequence GI 22125254. | Transmembrane component of cell wall structural complex MreBCD; COG2891; similar to AA sequence EcoGene EG10610; similar to AA sequence GI 77978747. | 0.658 |
| ftsQ | REG_1107 | REG_0710 | REG_1107 | Membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Hypothetical protein; COG1426; similar to AA sequence EcoGene EG10015; similar to AA sequence GI 77977353. | 0.503 |
| ftsQ | minC | REG_0710 | REG_0526 | Membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | 0.451 |
| ftsQ | mrdA | REG_0710 | REG_0613 | Membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Transpeptidase involved in peptidoglycan synthesis (penicillin-binding protein 2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.900 |
| ftsQ | mrdB | REG_0710 | REG_0614 | Membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.852 |
| ftsQ | mreB | REG_0710 | REG_1235 | Membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Actin-like component of cell wall structural complex MreBCD; COG1077; similar to AA sequence EcoGene EG10608; similar to AA sequence GI 62181882. | 0.482 |
| ftsQ | mreC | REG_0710 | REG_1236 | Membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Transmembrane component of cell wall structural complex MreBCD; COG1792; similar to AA sequence EcoGene EG10609; similar to AA sequence GI 145597589. | 0.557 |
| ftsQ | mreD | REG_0710 | REG_1237 | Membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | Transmembrane component of cell wall structural complex MreBCD; COG2891; similar to AA sequence EcoGene EG10610; similar to AA sequence GI 77978747. | 0.681 |
| minC | ftsQ | REG_0526 | REG_0710 | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.451 |
| minC | minD | REG_0526 | REG_0525 | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Septum formation inhibitor-activating ATPase; COG2894; similar to AA sequence EcoGene EG10597; similar to AA sequence GI 77962230. | 0.999 |
| minC | mreB | REG_0526 | REG_1235 | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Actin-like component of cell wall structural complex MreBCD; COG1077; similar to AA sequence EcoGene EG10608; similar to AA sequence GI 62181882. | 0.597 |
| minC | mreC | REG_0526 | REG_1236 | Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. | Transmembrane component of cell wall structural complex MreBCD; COG1792; similar to AA sequence EcoGene EG10609; similar to AA sequence GI 145597589. | 0.877 |