Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
mreDTransmembrane component of cell wall structural complex MreBCD; COG2891; similar to AA sequence EcoGene EG10610; similar to AA sequence GI 77978747. (162 aa)    
Predicted Functional Partners:
mreC
Transmembrane component of cell wall structural complex MreBCD; COG1792; similar to AA sequence EcoGene EG10609; similar to AA sequence GI 145597589.
  
 
 0.994
mreB
Actin-like component of cell wall structural complex MreBCD; COG1077; similar to AA sequence EcoGene EG10608; similar to AA sequence GI 62181882.
  
  
 0.930
minC
Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
  
  
 0.855
REG_1107
Hypothetical protein; COG1426; similar to AA sequence EcoGene EG10015; similar to AA sequence GI 77977353.
 
  
 0.830
mrdB
Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
  
 0.703
mrdA
Transpeptidase involved in peptidoglycan synthesis (penicillin-binding protein 2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
  
 0.695
rng
COG1530; similar to AA sequence EcoGene EG11299; similar to AA sequence GI 156935764.
       0.663
REG_1110
Hypothetical protein; COG2976; similar to AA sequence EcoGene EG14209; similar to AA sequence GI 22125254.
  
     0.658
ftsW
Integral membrane protein involved in stabilizing FstZ ring during cell division; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
  
  
 0.641
ftsQ
Membrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
  
  
 0.634
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
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