STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
degSSerine endoprotease; COG0265; similar to AA sequence EcoGene EG11652; similar to AA sequence GI 108809726. (350 aa)    
Predicted Functional Partners:
ompA
Outer membrane protein A; COG2885; similar to AA sequence EcoGene EG10669; similar to AA sequence GI 22126613.
    
 
 0.940
rseA
Anti-sigma factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading [...]
  
 
 0.935
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
    
 0.917
arcB
Hybrid sensory histidine kinase in two-component regulatory system with ArcA; COG0784; similar to AA sequence EcoGene EG10062; similar to AA sequence GI 77977063.
  
  
 0.815
alaS
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 
  0.804
kefB
Potassium:proton antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
     
 0.785
REG_1739
Hypothetical protein; COG3529; similar to AA sequence EcoGene EG14364; similar to AA sequence GI 77975003.
       0.773
ompN
Outer membrane pore protein N; Corrected polynucleotide track (1); COG3203; similar to AA sequence EcoGene EG13375; similar to AA sequence GI 123441874.
  
 
   0.660
REG_1018
ATPase domain-containing hypothetical protein; COG0464; similar to AA sequence GI 77165350.
    
 0.637
REG_0440
Lytic murein transglycosylase; COG0741; similar to AA sequence EcoGene EG10246; similar to AA sequence GI 123441269.
 
  
 0.606
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
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