Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
REG_2003Putative acetyltransferase; Similar to AA sequence GI 188533277. (150 aa)    
Predicted Functional Partners:
REG_2002
Hypothetical protein.
       0.709
thrA
Fused aspartokinase I and homoserine dehydrogenase I; COG0527; similar to AA sequence EcoGene EG10998; similar to AA sequence GI 123440965.
     
 0.552
dapE
N-succinyl-diaminopimelate deacylase; COG0624; similar to AA sequence EcoGene EG10208; similar to AA sequence GI 22125325.
  
 
 0.550
purL
Phosphoribosylformylglycinamide synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
     
 0.493
aspC
PLP-dependent aspartate aminotransferase; COG1448; similar to AA sequence EcoGene EG10096; similar to AA sequence GI 218548444.
     
 0.446
birA
biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
       0.416
purB
Adenylosuccinate lyase; COG0015; similar to AA sequence EcoGene EG11314; similar to AA sequence GI 77959454; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
  0.413
REG_0392
Predicted aminotransferase; COG0436; similar to AA sequence EcoGene EG14101; similar to AA sequence GI 21958421.
     
  0.410
gltA
Citrate synthase; COG0372; similar to AA sequence EcoGene EG10402; similar to AA sequence GI 157369505; Belongs to the citrate synthase family.
     
  0.410
pck
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
  0.410
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
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