STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
REG_2017Hypothetical protein; Corrected polynucleotide track (1), low coverage; similar to AA sequence GI 37528196. (192 aa)    
Predicted Functional Partners:
nuoI
NADH:ubiquinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 
 0.816
nuoC
NADH:ubiquinone oxidoreductase, chain C,D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
  
  
 0.735
fabG
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.664
sdhC
Succinate dehydrogenase membrane subunit 1 that binds cytochrome b556; COG2009; similar to AA sequence EcoGene EG10933; similar to AA sequence GI 22126947.
   
    0.643
fliM
Putative flagellar motor switch protein; Corrected polynucleotide tracks (3); similar to AA sequence GI 153949575.
    
   0.604
mdh
Malate dehydrogenase; COG0039; similar to AA sequence EcoGene EG10576; similar to AA sequence GI 123440795.
   
 
 0.579
REG_0973
Alpha/beta hydrolase domain-containing hypothetical protein; COG0596; similar to AA sequence EcoGene EG11776; similar to AA sequence GI 77976363.
  
 
 0.572
yfaE
2Fe-2S ferredoxin; COG0633; similar to AA sequence EcoGene EG12360; similar to AA sequence GI 77956356.
    
 0.554
birA
biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.548
REG_0392
Predicted aminotransferase; COG0436; similar to AA sequence EcoGene EG14101; similar to AA sequence GI 21958421.
  
  0.548
Your Current Organism:
Regiella insecticola
NCBI taxonomy Id: 663321
Other names: C. Regiella insecticola LSR1, Candidatus Regiella insecticola LSR1, Candidatus Regiella insecticola str. LSR1, Candidatus Regiella insecticola strain LSR1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.