STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKJ14593.1Hypothetical protein. (171 aa)    
Predicted Functional Partners:
AKJ14592.1
Sulfurtransferase.
  
    0.847
AKJ14591.1
ArsR family transcriptional regulator.
       0.767
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.718
AKJ12403.1
PTS sugar transporter subunit IIC.
    
  0.677
AKJ12564.1
M6 family metalloprotease domain protein.
    
   0.619
AKJ08994.1
Dimethylmenaquinone methyltransferase.
    
 0.584
AKJ14598.1
3-ketoacyl-ACP reductase.
  
    0.578
AKJ14415.1
Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate.
    
  0.553
AKJ08653.1
Aldehyde oxidase.
     
 0.523
hisF
Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
 
 0.523
Your Current Organism:
Streptomyces incarnatus
NCBI taxonomy Id: 665007
Other names: S. incarnatus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.