| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EAMY_2009 | pabB | EAMY_2009 | EAMY_2010 | Protein of unknown function UPF0181, Uncharacterised protein family (UPF0181); Belongs to the UPF0181 family. | Para-aminobenzoate synthase component 1 (Para-aminobenzoate synthase component I) (ADC synthase). | 0.598 |
| EAMY_2009 | sdaA | EAMY_2009 | EAMY_2012 | Protein of unknown function UPF0181, Uncharacterised protein family (UPF0181); Belongs to the UPF0181 family. | L-serine dehydratase 1 (L-serine deaminase 1) (SDH 1) (L-SD1), Iron-sulphur-dependent L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.420 |
| EAMY_2009 | yeaB | EAMY_2009 | EAMY_2011 | Protein of unknown function UPF0181, Uncharacterised protein family (UPF0181); Belongs to the UPF0181 family. | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.598 |
| birA | pabB | EAMY_0229 | EAMY_2010 | Biotin-protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Para-aminobenzoate synthase component 1 (Para-aminobenzoate synthase component I) (ADC synthase). | 0.420 |
| birA | yeaB | EAMY_0229 | EAMY_2011 | Biotin-protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.639 |
| birA | yjeF | EAMY_0229 | EAMY_3162 | Biotin-protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Uncharacterized protein yjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | 0.741 |
| pabB | EAMY_2009 | EAMY_2010 | EAMY_2009 | Para-aminobenzoate synthase component 1 (Para-aminobenzoate synthase component I) (ADC synthase). | Protein of unknown function UPF0181, Uncharacterised protein family (UPF0181); Belongs to the UPF0181 family. | 0.598 |
| pabB | birA | EAMY_2010 | EAMY_0229 | Para-aminobenzoate synthase component 1 (Para-aminobenzoate synthase component I) (ADC synthase). | Biotin-protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.420 |
| pabB | sdaA | EAMY_2010 | EAMY_2012 | Para-aminobenzoate synthase component 1 (Para-aminobenzoate synthase component I) (ADC synthase). | L-serine dehydratase 1 (L-serine deaminase 1) (SDH 1) (L-SD1), Iron-sulphur-dependent L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.602 |
| pabB | yeaB | EAMY_2010 | EAMY_2011 | Para-aminobenzoate synthase component 1 (Para-aminobenzoate synthase component I) (ADC synthase). | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.910 |
| sdaA | EAMY_2009 | EAMY_2012 | EAMY_2009 | L-serine dehydratase 1 (L-serine deaminase 1) (SDH 1) (L-SD1), Iron-sulphur-dependent L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Protein of unknown function UPF0181, Uncharacterised protein family (UPF0181); Belongs to the UPF0181 family. | 0.420 |
| sdaA | pabB | EAMY_2012 | EAMY_2010 | L-serine dehydratase 1 (L-serine deaminase 1) (SDH 1) (L-SD1), Iron-sulphur-dependent L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Para-aminobenzoate synthase component 1 (Para-aminobenzoate synthase component I) (ADC synthase). | 0.602 |
| sdaA | yeaB | EAMY_2012 | EAMY_2011 | L-serine dehydratase 1 (L-serine deaminase 1) (SDH 1) (L-SD1), Iron-sulphur-dependent L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.602 |
| vacB | yeaB | EAMY_3150 | EAMY_2011 | Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.440 |
| yeaB | EAMY_2009 | EAMY_2011 | EAMY_2009 | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Protein of unknown function UPF0181, Uncharacterised protein family (UPF0181); Belongs to the UPF0181 family. | 0.598 |
| yeaB | birA | EAMY_2011 | EAMY_0229 | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Biotin-protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.639 |
| yeaB | pabB | EAMY_2011 | EAMY_2010 | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Para-aminobenzoate synthase component 1 (Para-aminobenzoate synthase component I) (ADC synthase). | 0.910 |
| yeaB | sdaA | EAMY_2011 | EAMY_2012 | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | L-serine dehydratase 1 (L-serine deaminase 1) (SDH 1) (L-SD1), Iron-sulphur-dependent L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.602 |
| yeaB | vacB | EAMY_2011 | EAMY_3150 | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | 0.440 |
| yeaB | yjeF | EAMY_2011 | EAMY_3162 | Nudix hydrolase 15, mitochondrial precursor (AtNUDT15), NUDIX, NUDIX domain; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Uncharacterized protein yjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | 0.715 |