STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folEGTP cyclohydrolase I. (221 aa)    
Predicted Functional Partners:
folK
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK).
  
 0.995
ygcM
Putative 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (PTP synthase), 6-pyruvoyl tetrahydropterin synthase and hypothetical protein, 6-pyruvoyl tetrahydropterin synthase, 6PTHBS: putative 6-pyruvoyl tetrahydropterin synthase.
  
 
 0.979
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
 
 
 
 0.964
folP
7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.955
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
  0.907
ntpA
dATP pyrophosphohydrolase; NUDIX, NUDIX domain.
    
  0.907
phoA
Alkaline phosphatase precursor (APase); Belongs to the alkaline phosphatase family.
   
 
  0.900
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.836
mazG
Protein mazG; NTP pyrophosphohydrolase MazG, bacterial, MazG nucleotide pyrophosphohydrolase domain, mazG: MazG family protein.
    
 0.833
yeiB
Uncharacterized protein yeiB; Protein of unknown function DUF418, Protein of unknown function (DUF405).
     
 0.813
Your Current Organism:
Erwinia amylovora
NCBI taxonomy Id: 665029
Other names: E. amylovora CFBP1430, Erwinia amylovora CFBP1430, Erwinia amylovora str. CFBP1430, Erwinia amylovora strain CFBP1430
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