STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrcA3.4.-.-], Penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin-insensitive transglycosylase (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (DD-transpeptidase)], Penicillin-binding protein 1A, Transglycosylase, PBP_1a_fam: penicillin-binding protein, 1A family. (848 aa)    
Predicted Functional Partners:
mrcB
Peptidoglycan synthetase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
 
0.952
dacA
D-alanyl-D-alanine carboxypeptidase, fraction A; Penicillin-binding protein 6B precursor (DD-peptidase) (DD-carboxypeptidase) (PBP-6B); Belongs to the peptidase S11 family.
     
 0.914
dacC
D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 6B precursor (DD-peptidase) (DD-carboxypeptidase) (PBP-6B), Beta-lactamase-type transpeptidase fold, D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.914
hofQ
Protein transport protein hofQ precursor; Predicted fimbrial transporter, outer membrane porin HofQ.
     
 0.845
hofN
Fimbrial assembly protein hofN.
       0.842
yraM
Uncharacterized protein yraM; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.
  
 
 
 0.706
gltB
Glutamate synthase.
       0.672
murC
L-alanine adding enzyme, UDP-N-acetyl-muramate:alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
   
 0.667
hofM
Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]'.
     
 0.640
EAMY_3434
Conserved membrane protein hofO.
       0.622
Your Current Organism:
Erwinia amylovora
NCBI taxonomy Id: 665029
Other names: E. amylovora CFBP1430, Erwinia amylovora CFBP1430, Erwinia amylovora str. CFBP1430, Erwinia amylovora strain CFBP1430
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