STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFZ81561.13-hydroxyisobutyrate dehydrogenase. (318 aa)    
Predicted Functional Partners:
SFZ84734.1
Malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase.
 
 
 0.869
SFZ83698.1
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.818
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.799
SFZ85155.1
D-lactate dehydrogenase.
    
  0.798
SFZ83084.1
3-oxoadipate enol-lactonase.
  
 
 0.760
SFZ81563.1
Xaa-Pro aminopeptidase.
 
     0.681
SFZ83041.1
Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 
 0.626
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
  0.605
acsA-2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
  0.605
SFZ85477.1
4-hydroxy-2-oxoheptanedioate aldolase; Belongs to the HpcH/HpaI aldolase family.
  
 
  0.583
Your Current Organism:
Devosia enhydra
NCBI taxonomy Id: 665118
Other names: ATCC 23634, D. enhydra, JCM 21106, NBRC 102409, Prosthecomicrobium enhydrum, Vasilyevaea enhydra, Vasilyevea enhydrum, strain 9b
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