STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFZ82293.1CBS domain-containing protein. (142 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
    
 0.964
SFZ86654.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.946
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.940
SFZ86202.1
PAS domain S-box-containing protein.
    
 0.880
SFZ81913.1
PAS domain S-box-containing protein.
    
 0.794
SFZ84857.1
Dihydropyrimidine dehydrogenase (NAD+) subunit PreA.
  
 
 0.715
SFZ83212.1
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
     
  0.698
SFZ81458.1
Two-component system, cell cycle sensor histidine kinase and response regulator CckA.
    
 0.687
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.646
SFZ80983.1
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.626
Your Current Organism:
Devosia enhydra
NCBI taxonomy Id: 665118
Other names: ATCC 23634, D. enhydra, JCM 21106, NBRC 102409, Prosthecomicrobium enhydrum, Vasilyevaea enhydra, Vasilyevea enhydrum, strain 9b
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.