STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFZ82382.1Exodeoxyribonuclease-3. (259 aa)    
Predicted Functional Partners:
nth
DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.969
SFZ84967.1
DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...]
   
 0.877
SFZ86098.1
A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.857
SFZ85723.1
DNA-3-methyladenine glycosylase II.
   
 0.852
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.843
SFZ81264.1
Bifunctional non-homologous end joining protein LigD.
  
 
 0.780
SFZ81688.1
DNA polymerase-1.
   
 0.755
hfq
Host factor-I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
    
 
 0.737
SFZ85223.1
Exodeoxyribonuclease-3.
  
  
 
0.736
SFZ83709.1
DNA ligase-1.
  
 
 0.731
Your Current Organism:
Devosia enhydra
NCBI taxonomy Id: 665118
Other names: ATCC 23634, D. enhydra, JCM 21106, NBRC 102409, Prosthecomicrobium enhydrum, Vasilyevaea enhydra, Vasilyevea enhydrum, strain 9b
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.