node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFZ80807.1 | SFZ85503.1 | SAMN02983003_0145 | SAMN02983003_2668 | RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family. | Hypothetical chaperone protein. | 0.993 |
SFZ80807.1 | acpP | SAMN02983003_0145 | SAMN02983003_0182 | RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.986 |
SFZ80807.1 | dnaJ | SAMN02983003_0145 | SAMN02983003_2335 | RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.875 |
SFZ80807.1 | dnaK | SAMN02983003_0145 | SAMN02983003_2333 | RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.993 |
SFZ80807.1 | groL | SAMN02983003_0145 | SAMN02983003_3333 | RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.963 |
SFZ80807.1 | grpE | SAMN02983003_0145 | SAMN02983003_2295 | RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.566 |
SFZ80807.1 | rplC | SAMN02983003_0145 | SAMN02983003_0309 | RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.573 |
SFZ80807.1 | rplN | SAMN02983003_0145 | SAMN02983003_0319 | RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family. | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.601 |
SFZ85503.1 | SFZ80807.1 | SAMN02983003_2668 | SAMN02983003_0145 | Hypothetical chaperone protein. | RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family. | 0.993 |
SFZ85503.1 | dnaJ | SAMN02983003_2668 | SAMN02983003_2335 | Hypothetical chaperone protein. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.975 |
SFZ85503.1 | groL | SAMN02983003_2668 | SAMN02983003_3333 | Hypothetical chaperone protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.959 |
SFZ85503.1 | grpE | SAMN02983003_2668 | SAMN02983003_2295 | Hypothetical chaperone protein. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.995 |
SFZ85503.1 | hslU | SAMN02983003_2668 | SAMN02983003_2355 | Hypothetical chaperone protein. | ATP-dependent HslUV protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.656 |
SFZ85503.1 | rplC | SAMN02983003_2668 | SAMN02983003_0309 | Hypothetical chaperone protein. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.723 |
SFZ85503.1 | rplN | SAMN02983003_2668 | SAMN02983003_0319 | Hypothetical chaperone protein. | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.785 |
acpP | SFZ80807.1 | SAMN02983003_0182 | SAMN02983003_0145 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | RNA polymerase primary sigma factor; Belongs to the sigma-70 factor family. | 0.986 |
acpP | dnaJ | SAMN02983003_0182 | SAMN02983003_2335 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.854 |
acpP | groL | SAMN02983003_0182 | SAMN02983003_3333 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.498 |
acpP | rplC | SAMN02983003_0182 | SAMN02983003_0309 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.982 |
acpP | rplN | SAMN02983003_0182 | SAMN02983003_0319 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.988 |