STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPL51396.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)    
Predicted Functional Partners:
KPL54078.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.934
KPL51395.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.709
KPL56061.1
NADH-quinone oxidoreductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.691
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.539
KPL51352.1
Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.521
KPL50784.1
NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
   
    0.521
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.494
KPL55645.1
Magnesium-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.488
Your Current Organism:
Prosthecomicrobium hirschii
NCBI taxonomy Id: 665126
Other names: ATCC 27832, P. hirschii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.