STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPL51405.1Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family. (510 aa)    
Predicted Functional Partners:
KPL54548.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family.
  
  
 
0.837
KPL51862.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.803
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.785
KPL51404.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
KPL54051.1
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.713
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 
  0.670
KPL51407.1
Hypothetical protein; HflC and HflK could regulate a protease.
 
 
 0.646
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
  
 0.620
KPL51408.1
Hypothetical protein; HflC and HflK could encode or regulate a protease.
 
 
 0.615
KPL54196.1
Ornithine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
  
  0.598
Your Current Organism:
Prosthecomicrobium hirschii
NCBI taxonomy Id: 665126
Other names: ATCC 27832, P. hirschii
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