STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPL52185.1Flagellar motor protein MotA; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)    
Predicted Functional Partners:
KPL52186.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.958
parC
DNA topoisomerase IV; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
 
 0.943
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.935
KPL55626.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.927
KPL51512.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.927
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
   0.927
KPL51506.1
Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.924
KPL52187.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.817
KPL52188.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.790
KPL52184.1
Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the inositol monophosphatase superfamily.
       0.564
Your Current Organism:
Prosthecomicrobium hirschii
NCBI taxonomy Id: 665126
Other names: ATCC 27832, P. hirschii
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