STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KPL52358.1Methylenetetrahydromethanopterin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)    
Predicted Functional Partners:
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
  
 0.986
KPL52361.1
Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.979
KPL56167.1
Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.959
KPL52357.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.927
KPL55626.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.924
KPL55762.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.923
KPL52360.1
triphosphoribosyl-dephospho-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.896
KPL55763.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RimK family.
 
     0.888
KPL52356.1
Pterin dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.885
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.815
Your Current Organism:
Prosthecomicrobium hirschii
NCBI taxonomy Id: 665126
Other names: ATCC 27832, P. hirschii
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