KPL55046.1 protein (Prosthecomicrobium hirschii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KPL55046.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)

Predicted Functional Partners:

KPL56123.1

0.999

KPL55078.1

0.986

KPL51165.1

0.938

KPL55082.1

0.938

KPL54778.1

0.934

KPL53901.1

0.921

KPL55079.1

0.920

KPL53019.1

0.919

KPL51904.1

0.918

KPL51626.1

0.834

Your Current Organism:

Prosthecomicrobium hirschii

NCBI taxonomy Id: 665126
Other names: ATCC 27832, P. hirschii

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KPL51165.1	KPL51904.1	ABB55_02140	ABB55_06415	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.875
KPL51165.1	KPL53019.1	ABB55_02140	ABB55_12985	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
KPL51165.1	KPL53901.1	ABB55_02140	ABB55_18185	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.904
KPL51165.1	KPL55046.1	ABB55_02140	ABB55_24800	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.938
KPL51165.1	KPL55078.1	ABB55_02140	ABB55_24990	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.971
KPL51165.1	KPL55079.1	ABB55_02140	ABB55_24995	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.901
KPL51165.1	KPL56123.1	ABB55_02140	ABB55_24985	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.972
KPL51626.1	KPL55046.1	ABB55_04760	ABB55_24800	Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.834
KPL51626.1	KPL55078.1	ABB55_04760	ABB55_24990	Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.428
KPL51626.1	KPL56123.1	ABB55_04760	ABB55_24985	Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.408
KPL51904.1	KPL51165.1	ABB55_06415	ABB55_02140	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.875
KPL51904.1	KPL54778.1	ABB55_06415	ABB55_23235	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.837
KPL51904.1	KPL55046.1	ABB55_06415	ABB55_24800	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
KPL51904.1	KPL55078.1	ABB55_06415	ABB55_24990	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.936
KPL51904.1	KPL55082.1	ABB55_06415	ABB55_25010	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.899
KPL51904.1	KPL56123.1	ABB55_06415	ABB55_24985	Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.918
KPL53019.1	KPL51165.1	ABB55_12985	ABB55_02140	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
KPL53019.1	KPL54778.1	ABB55_12985	ABB55_23235	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.863
KPL53019.1	KPL55046.1	ABB55_12985	ABB55_24800	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.919
KPL53019.1	KPL55078.1	ABB55_12985	ABB55_24990	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.937

page 1 of 4

Network Stats

number of nodes:

6

number of edges:

13

average node degree:

4.33

avg. local clustering coefficient:

0.9

expected number of edges:

5

PPI enrichment p-value:

0.00201

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009168

Purine ribonucleoside monophosphate biosynthetic process

7 of 18

1.88

3.49

2.80e-09

GO:0006189

De novo IMP biosynthetic process

6 of 13

1.96

3.49

8.61e-09

GO:0009152

Purine ribonucleotide biosynthetic process

7 of 35

1.6

2.69

8.99e-09

GO:0009260

Ribonucleotide biosynthetic process

8 of 47

1.53

2.6

2.80e-09

GO:0044208

De novo AMP biosynthetic process

2 of 2

2.29

1.42

0.0022

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

5 of 35

1.45

1.4

0.00029

GO:0016742

Hydroxymethyl-, formyl- and related transferase activity

2 of 3

2.12

0.81

0.0319

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 98

1.0

0.75

0.0039

GO:0005622

Intracellular anatomical structure

11 of 680

0.5

0.43

0.00030

GO:0005737

Cytoplasm

9 of 557

0.5

0.38

0.0055

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:946

De novo IMP biosynthetic process

7 of 11

2.1

4.44

8.92e-11

CL:828

Cellular amino acid biosynthetic process, and Ribonucleoside monophosphate biosynthetic process

8 of 105

1.18

1.48

4.72e-07

CL:948

Phosphoribosylformylglycinamidine synthase activity, and PurE domain

2 of 6

1.82

0.78

0.0315

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

7 of 45

1.49

2.25

8.35e-08

map00670

One carbon pool by folate

2 of 6

1.82

0.93

0.0149

map00250

Alanine, aspartate and glutamate metabolism

3 of 25

1.37

0.84

0.0125

map01110

Biosynthesis of secondary metabolites

7 of 313

0.64

0.44

0.0125

map01100

Metabolic pathways

9 of 679

0.42

0.31

0.0160

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0658

Purine biosynthesis

5 of 11

1.95

2.81

6.58e-07

KW-0436

Ligase

5 of 56

1.25

1.16

0.00040

KW-0460

Magnesium

4 of 45

1.24

0.96

0.0030

KW-0315

Glutamine amidotransferase

2 of 12

1.52

0.64

0.0496

KW-0547

Nucleotide-binding

5 of 145

0.83

0.54

0.0162

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (28%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About