node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
M2RKM7_COCSN | M2RM56_COCSN | M2RKM7 | M2RM56 | Nucleoside diphosphate kinase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.987 |
M2RKM7_COCSN | M2RY73_COCSN | M2RKM7 | M2RY73 | Nucleoside diphosphate kinase. | Flavoprotein domain-containing protein. | 0.744 |
M2RKM7_COCSN | M2SKY1_COCSN | M2RKM7 | M2SKY1 | Nucleoside diphosphate kinase. | dUTPase domain-containing protein. | 0.980 |
M2RKM7_COCSN | M2SL87_COCSN | M2RKM7 | M2SL87 | Nucleoside diphosphate kinase. | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | 0.422 |
M2RKM7_COCSN | M2SMF9_COCSN | M2RKM7 | M2SMF9 | Nucleoside diphosphate kinase. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.989 |
M2RKM7_COCSN | M2T690_COCSN | M2RKM7 | M2T690 | Nucleoside diphosphate kinase. | Flavoprotein domain-containing protein. | 0.744 |
M2RM56_COCSN | M2RKM7_COCSN | M2RM56 | M2RKM7 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nucleoside diphosphate kinase. | 0.987 |
M2RM56_COCSN | M2RY73_COCSN | M2RM56 | M2RY73 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Flavoprotein domain-containing protein. | 0.733 |
M2RM56_COCSN | M2SKY1_COCSN | M2RM56 | M2SKY1 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | dUTPase domain-containing protein. | 0.945 |
M2RM56_COCSN | M2SL87_COCSN | M2RM56 | M2SL87 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein; Belongs to the 5'-nucleotidase family. | 0.901 |
M2RM56_COCSN | M2SMF9_COCSN | M2RM56 | M2SMF9 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.748 |
M2RM56_COCSN | M2T690_COCSN | M2RM56 | M2T690 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Flavoprotein domain-containing protein. | 0.733 |
M2RM56_COCSN | M2T6C6_COCSN | M2RM56 | M2T6C6 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Thymidylat_synt domain-containing protein. | 0.715 |
M2RM56_COCSN | M2T6I0_COCSN | M2RM56 | M2T6I0 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | SurE domain-containing protein. | 0.900 |
M2RY73_COCSN | M2RKM7_COCSN | M2RY73 | M2RKM7 | Flavoprotein domain-containing protein. | Nucleoside diphosphate kinase. | 0.744 |
M2RY73_COCSN | M2RM56_COCSN | M2RY73 | M2RM56 | Flavoprotein domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.733 |
M2RY73_COCSN | M2SKY1_COCSN | M2RY73 | M2SKY1 | Flavoprotein domain-containing protein. | dUTPase domain-containing protein. | 0.958 |
M2RY73_COCSN | M2SMF9_COCSN | M2RY73 | M2SMF9 | Flavoprotein domain-containing protein. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.813 |
M2RY73_COCSN | M2T690_COCSN | M2RY73 | M2T690 | Flavoprotein domain-containing protein. | Flavoprotein domain-containing protein. | 0.434 |
M2RY73_COCSN | M2T6C6_COCSN | M2RY73 | M2T6C6 | Flavoprotein domain-containing protein. | Thymidylat_synt domain-containing protein. | 0.469 |