node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KAE1 | M2RV61_COCSN | M2TF30 | M2RV61 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | Protein kinase domain-containing protein. | 0.998 |
KAE1 | M2SR32_COCSN | M2TF30 | M2SR32 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | 0.998 |
KAE1 | M2SSY5_COCSN | M2TF30 | M2SSY5 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.431 |
KAE1 | M2TCH2_COCSN | M2TF30 | M2TCH2 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | YrdC-like domain-containing protein. | 0.884 |
M2RV61_COCSN | KAE1 | M2RV61 | M2TF30 | Protein kinase domain-containing protein. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.998 |
M2RV61_COCSN | M2SR32_COCSN | M2RV61 | M2SR32 | Protein kinase domain-containing protein. | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | 0.998 |
M2RV61_COCSN | M2SSY5_COCSN | M2RV61 | M2SSY5 | Protein kinase domain-containing protein. | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.956 |
M2RV61_COCSN | M2TCH2_COCSN | M2RV61 | M2TCH2 | Protein kinase domain-containing protein. | YrdC-like domain-containing protein. | 0.644 |
M2RX25_COCSN | M2SR32_COCSN | M2RX25 | M2SR32 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | 0.565 |
M2RX25_COCSN | M2T9R3_COCSN | M2RX25 | M2T9R3 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. | 0.473 |
M2SR32_COCSN | KAE1 | M2SR32 | M2TF30 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.998 |
M2SR32_COCSN | M2RV61_COCSN | M2SR32 | M2RV61 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | Protein kinase domain-containing protein. | 0.998 |
M2SR32_COCSN | M2RX25_COCSN | M2SR32 | M2RX25 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.565 |
M2SR32_COCSN | M2SSY5_COCSN | M2SR32 | M2SSY5 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.957 |
M2SR32_COCSN | M2T9R3_COCSN | M2SR32 | M2T9R3 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. | 0.592 |
M2SR32_COCSN | M2TCH2_COCSN | M2SR32 | M2TCH2 | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | YrdC-like domain-containing protein. | 0.642 |
M2SSY5_COCSN | KAE1 | M2SSY5 | M2TF30 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] | 0.431 |
M2SSY5_COCSN | M2RV61_COCSN | M2SSY5 | M2RV61 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | Protein kinase domain-containing protein. | 0.956 |
M2SSY5_COCSN | M2SR32_COCSN | M2SSY5 | M2SR32 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | Uncharacterized protein; Belongs to the CGI121/TPRKB family. | 0.957 |
M2SSY5_COCSN | M2TCH2_COCSN | M2SSY5 | M2TCH2 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | YrdC-like domain-containing protein. | 0.884 |